ICSI · Gurugram

ICSI — when sperm need a helping hand

Intracytoplasmic Sperm Injection: a single, precisely selected sperm injected directly into the egg. The gold-standard answer to severe male factor infertility.

4.9 · Google · 500+ reviews
ICSI (Intracytoplasmic Sperm Injection)
Dr. Parul Katiyar

Quick facts

Cycle duration

4–6 weeks

Sperm injected

1 per egg

Fertilisation rate

70–80%

Hospital stay

Day-care

Anaesthesia

Mild sedation

Live-birth rate

Comparable to IVF

Overview

An overview of ICSI

ICSI (Intracytoplasmic Sperm Injection) is a micromanipulation technique used during IVF where a single, motile, morphologically normal sperm is injected directly into the cytoplasm of a mature egg using a fine glass needle under a high-magnification microscope.

Who needs ICSI?

Eligibility criteria we evaluate at the first consultation.

Severe male factor

Oligospermia, asthenospermia, or teratospermia on semen analysis.

Azoospermia

Sperm retrieved surgically via PESA, TESA or microTESE.

Prior fertilisation failure

Less than 30% fertilisation in a previous IVF cycle.

Frozen / thawed sperm

When sperm motility is reduced post-thaw.

Limited egg numbers

Optimises fertilisation when only few eggs are available.

PGT cycles

Prevents extraneous sperm DNA from contaminating biopsy results.

How ICSI works — step by step

ICSI follows the same stimulation + retrieval as IVF, with an additional micromanipulation step in the lab.

  1. 1

    Stimulation & retrieval

    Day 1–13

    Same as IVF — daily injections to mature multiple follicles, then transvaginal egg retrieval.

  2. 2

    Sperm preparation

    Day 13

    Sperm sample washed and the most motile, morphologically normal sperm selected under high magnification.

  3. 3

    Egg denudation

    Day 13

    Surrounding cumulus cells removed so only mature (MII) eggs are injected.

  4. 4

    ICSI micromanipulation

    Day 13

    A single sperm injected directly into each mature egg using a glass micropipette under an inverted microscope.

  5. 5

    Embryo culture

    Day 14–18

    Embryos cultured to blastocyst stage in time-lapse Embryoscope.

  6. 6

    Embryo transfer

    Day 18–20

    Single embryo transfer, fresh or frozen.

Success rates

Our outcomes vs national averages.

Fertilisation rate

70–80%

Per mature egg injected

Blastulation rate

45–55%

By Day 5

Live birth < 35y

52%

Per transfer

Live birth 38–40y

26%

Per transfer

Individual outcomes vary. We provide a personalised prognosis at consultation.

Risks & side effects

Lab technology we use

Technology

Time-Lapse Embryoscope

Continuous embryo monitoring without removing them from the incubator.

Technology

RI Witness

RFID identification system that prevents specimen mix-ups across the IVF workflow.

Technology

Laser-Assisted Hatching

Precision laser hatching of the zona pellucida to support implantation.

Dr. Parul Katiyar

Meet your doctor

Dr. Parul Katiyar

Senior IVF & Fertility Specialist · 20+ years · 5,000+ cycles

  • 🎓 MSc Reproductive Medicine, University of Valencia (Spain)
  • 🩺 Clinical training, Yale Medical School (USA) & Androfert (Brazil)
  • 🏆 ISAR, FOGSI, ESHRE, ASRM member
  • 🌍 Speaks English, Hindi · Treats patients globally

Patient stories

“After three failed cycles at another clinic, Dr. Parul re-investigated everything. Her protocol gave us our daughter, Aarna. She didn't just treat us — she believed in us.”

Priya & Rohan, Delhi

IVF after 7 years of trying

“We travelled from Suva. The team handled everything — visa support, accommodation, even translation. Our son arrived in November.”

Suva & Anish, Fiji

International Patient — ICSI

“I almost gave up. Dr. Parul's PCOS program changed my life — physically and emotionally. Forever grateful.”

Rahima, Dhaka

PCOS Fertility Program

Frequently asked questions

Take the first step today

A personal consultation with Dr. Parul Katiyar costs ₹2,000 — and clarifies more than a year of Googling.

Quick enquiry

Your information is private and never shared. We respond within 24 hours.